Pharmaceutical raw powder Bun Dexbudesonide
Product Name: 16a(R),17-(Butylidenebis(oxy))-11b,21-dihydroxypregna-1,4-diene-3,20-dione
Synonyms: 16a(r),17-(butylidenebis(oxy))-11b,21-dihydroxypregna-1,4-diene-3,20-dione;(r)-budesonide;(22R)-Budesonide;16α,17-[(R)-Butylidenebisoxy]-11β,21-dihydroxypregna-1,4-diene-3,20-dione;(22R)-Budesonide (>90% de);Dexbudesonide;(11β,16α)-;TriaMcinolone-d5
CAS: 51372-29-3
MF: C25H34O6
MW: 430.53
EINECS: 257-161-7
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
mp 194-199°C
storage temp. -20°C Freezer
Chemical Properties Light Beige Solid
Usage Budesonide (B689490) epimer R
Usage Labelled Triamcinolone. Triamcinolone is a glucocorticoid. Triamcinolone is used as an antiasthmatic (inhalant); antiallergic (nasal).
Product Description:
BUN is a highly effective topical anti-inflammatory effects of glucocorticoid. It can enhance the endothelial cells, smooth muscle cells and the lysosome membrane stability, suppress the immune response and reduce the synthesis of antibodies, which makes the release of histamine and other allergic active medium to reduce and activity is reduced, and can reduce the antigen antibody when combined excitation of enzymatic process, and the synthesis and release of bronchoconstriction substances reduce smooth muscle contraction. Acute, subacute and chronic toxicity studies have found that the product of the whole body, such as weight loss, lymphoid tissue and adrenal cortical atrophy and weaker than other glucocorticoids or equivalent.
Applications/Usage:
1.Nose drops for seasonal and chronic allergic rhinitis, vasomotor rhinitis, nasal polyp prevention polyps regeneration after resection
2.Aerosol for chronic asthma
3.Topical formulations used in skin inflammatory disease
4.Capsule: the treatment for mild to moderate active crohn's disease.
5.Used for glucocorticoid dependence or independence in patients with chronic bronchitis, bronchial asthma and asthma.
6.Mild, moderate crohn, ulcerative colitis, colon limited available this enema in the sigmoid colon.
7.Labelled Triamcinolone. Triamcinolone is a glucocorticoid. Triamcinolone is used as an antiasthmatic (inhalant); antiallergic (nasal).
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