Product Description

Product Name: Isotretinoin (Roaccutane),Accutane
Synonyms:Isoretinoin;isotrex;neovitaminaacid;roaccutane;teriosal;Lsotretinoin
CAS No.: 4759-48-2
EINECS No.: 225-296-0
Molecular Formula: C20H28O2
Molecular Weight: 300.44
Purity:99%
Appearance: orange red crystal
Grade:Pharmaceutical grade

Isotretinoin (Accutane) is primarily used to treat bad cases of cystic acne, and to help the skin more rapidly renew itself. In addition, it is used in rare cases for certain skin cancers and skin diseases. It is a type of retinoid, which is naturally found in the body in small amounts.

Description

Isotretinoin (13-cis-Retinoic acid )is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. Clinically, 13-cis-Retinoic acid is primarily used in the treatment of severe recalcitrant nodular acne. Its effects include reducing the production of sebum, shrinking the size of the sebaceous glands, stabilizing keratinization, preventing comedones from forming, and reducing inflammation of inflammatory acne. Though the exact mechanism of action of 13-cis-Retinoic acid is not fully understood, studies have suggested that the compound alters DNA transcription and induces apoptosis in select types of cells throughout the body.

Function

Both tretionirum and Vitamin A can stimulate skin growth and keep epidermic normal. Howerver, to spread on part of skin has no actual effect. Taking orally vitamin A is benefit to treat skin disorders. Applying vitamin A acid to skin partly could produce intensive pharmacological action. External use can slow down skin aging process for solarization, remove tiny wrinkles, and reduce skin roughness, so skin will become ruddy.

Side-effect and Notice

Don`t spread it in thin skin. Proper lower concentration (no more than 0.025%)can avoid such reaction as scalp off, Scorching fever and erythema, which is caused by drastic dilation of blood vessel. Please insist on using the product and you will get preferable curative effect when you find such normal reaction as erythema, scorch fever and hypodynia. Discontinue it and apply some oleiferous skin-care products to the skin site, if the reaction is severe. Cold cream concentration less than 0.025, show some effect upon treating acne and skin roughness kept cool and closed.

Application

Isotretinoin, Vitamin A class drugs. It can rapidly and strongly inhibit the cell proliferation and differentiation process of skin glands cells. It has a high effect on severe nodular cystic acne. This product has a high gastrointestinal absorption, but invalid for topical administration. It is used for treating severe acnes which cannot be treated by other drugs. It also has some effects on treating cystic acne, the party of acne, rosacea, ichthyosis, follicular keratosis and pityriasis red hair and other skin diseases.

1. It is a drug commonly used to treat acne vulgaris and keratosis pilaris.

2. It is available as a cream or gel. It is also used to treat acute promyelocytic leukemia.

3. It can stimulate skin growth and keep epidermic normal.

4. It can slow down skin aging process for solarization, remove tiny wrinkles.

5. It can reduce skin roughness, so skin will become ruddy.

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