Piperonyl butoxide

Piperonyl butoxide (PBO) CAS 51-03-6 Injurious insect killer harmless workable synergist 

Piperonyl butoxide

Alias: PBO

CAS: 51-03-6

MF: C19H30O5

MW: 338.44

Flash Point(o C): 253.8° C

Boiling Point(o C): 496.1° C at 760 mmHg

CAS: 51-03-6

Appearance: Light yellow clear liquid

Water Solubility: <0.1 g/100 mL at 18o C

Usage: Piperonyl butoxide is a component of pesticide formulations and synthetic insecticide synergist. Piperonyl butoxide does not have insecticidal activity

Piperonyl butoxide is combined with other pesticides such as pyrethroids, pyrethrins, rotenone and carbamates to enhance their effectiveness.

Piperonyl butoxide mixtures are often used on livestock and food crops. It is also found in a wide range of household insecticides such as sprays and lice treatment shampoos.

Piperonyl butoxide (PBO) is an insecticide synergist. It acts by protecting the co- applied insecticide (e.g. pyrethrins, pyrethroids and other pesticides) from metabolic attack thus allowing them to reach their biochemical targets. Since piperonyl butoxide inhibits an enzyme system which is catalysing oxidative processes in living systems, it also has an intrinsic toxic potential to arthropods. It is widely used in combination with pyrethrins, pyrethroids and other pesticides, in public health, household and human and veterinary medicinal products, agriculture, stored product protection, home and garden, etc. against a variety of flying and crawling arthropod species, e.g. mosquitoes, houseflies, cockroaches, storage pests, mites, moths, ticks, lice, etc.

Piperonyl butoxide is a potent inhibitor of cytochrome P450 enzymes, which detoxify insecticides for many pests. Therefore, inhibiting the P450s allows higher unmetabolised systemic concentrations of the insecticide (such as pyrethroid) to remain within the target animal for a longer period.