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Diclofenac sodium
Diclofenac sodium
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Place of Origin:
China
Brand Name:
Saichuang
Model Number:
15307-79-6
Packaging & Delivery
Product Description

Product Description

[English Name]Diclofenac sodium

[Test Method]HPLC

[Purity]≥99%

[Synonyms] Neriodin

[CAS No.]15307-79-6

[Mol. Formula]C14H10Cl2NNaO2

[Mol. Weight]318.14

[Purity]> 99% by HPLC

[Packaging] 25 KG/Drum

Package and quantity according to customer's detail requirement

[Remark] In stock, customized for large scale.

 

 

 Description

Diclofenac (sold under a number of trade names) is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. It is supplied as or contained in medications under a variety of trade names.
The name "diclofenac" derives from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid. Diclofenac was first synthesized by Alfred Sallmann and Rudolf Pfister and introduced as Voltaren by Ciba-Geigy (now Novartis) in 1973.
In the United Kingdom, United States, India, and Brazil diclofenac may be supplied as either the sodium or potassium salt; in China, it is most often supplied as the sodium salt, while in some other countries it is only available as the potassium salt. It is available as a generic drug in a number of formulations, including diclofenac diethylamine, which is applied topically. Over-the-counter (OTC) use is approved in some countries for minor aches and pains and fever associated with common infections.

 

Applications

  •  Acute and chronic rheumatoid arthritis, acute and chronic arthritis, acute and chronic ankylosing spondylitis, and osteoarthritis.

  •  Periarthritis, bursitis, tendonitis and tenosynovitis.

  •  Low back pain, sprains, strains and other soft tissue injuries.

  • Acute gout.

  • Dysmenorrhea or attachment inflammation, toothache and postoperative pain.

  • Post-traumatic pain and inflammation, such as sprains, muscle strains, etc.;

  • Severe otolaryngological infection pain and inflammation (such as tonsillitis, otitis, sinusitis, etc.) should be combined with anti-infective drugs.

 

Function

1.This product is a synthetic prostaglandin F2a homologue.
2.Strong the function of dissolving luteal; It can quickly cause corpus luteum regression, and suppress the secretion;
3. Have direct excitation effect on uterine smooth muscle; It can cause uterine smooth muscle contraction, cervical relaxation.
4.For sexual cycle normal animals, usually Estrus in 2 ~ 5 days after heat treatment.

 

Specifications

COA

ItemSpecificationResult
AppearanceA white or slightly yellowish crystalline powderWhite crystalline powder
IdentificationA.IR

B.HPLC

C.test of sodium salt

Accord

Accord

Conform

Appearance of Solution5.0% of methanol solution 440nm, nmt0.050.011
Melting point288-290℃Conform
Clarity of solutionEqual to methanolPass
PH6.5~7.57.2
Related substanceIndividual impurity: 0.02%max

Total inpurities:0.5%max

Individual impurity: 0.01%max

total impurities: 0.4%max

Chloride≤0.02%≤0.01%
Heavy metal10ppm9ppm
Assay(by HPLC)≥98.5%≥99.5%
Assay≥98.0%≥99.0%

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